产品货号：
Z25003
中文名称：
RASGAP/RASA1抗体
英文名称：
Anti-RASGAP/RASA1 Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-RASGAP/RASA1 Antibody |
| 指标别名 | CM AVM;CMAVM;GAP;GTPase activating protein;p120GAP;p120RASGAP;PKWS;Ras p21 protein activator;RASA;RASA1;RASGAP |
| 克隆性 | Polyclonal |
| 检验物种 | human,rat |
| 应用范围 | WB,ELISA |
| 基因名称 | RASA1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 计算分子量 | 116KD |
| 成分 | Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide. |
| 纯化方式 | RASA1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | RASA1,also known as RAS p21 protein activator 1,is a 120-kDacytosolic human protein.The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins.The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart.Acting as a suppressor of RAS function,the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS,thereby allowing control of cellular proliferation and differentiation.Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas.Mutations also have been associated with hereditary capillary malformations (CM) with or without arteriovenous malformations (AVM) and Parkes Weber syndrome.Alternative splicing results in two isoforms where the shorter isoform,lacking the N-terminal hydrophobic region but retaining the same activity,appears to be abundantly expressed in placental but not adult tissues. |
| Uniprot ID | P20936 |
| 基因名全称 | Ras GTPase-activating protein 1 |
| 蛋白名全称 | Ras GTPase-activating protein 1 |
| 推荐稀释比 | WB 1:500～2000 ELISA 1:5000～20000 |
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